New findings of Dengue Fever could help with vaccine

Dengue fever also known as “breakbone” or “dandyfever” could be described as an acute illness which could catch a person unknowingly. This condition shows symptoms like fever, headache, severe joint and muscle pain, rashes and exhaustion. People with low level of immunity are prone to this condition. This disease is usually caused by one of the four serotypes of viruses. A person can catch dengue fever multiple times, but this attack generate immunity for lifelong to that particular serotype for which the patient was exposed. A person can get dengue virus when Aedes aegypti from the mosquito bite which has previously bitten an infected person. Mosquitoes usually originate during rainy seasons and can breed in water-filled flower pits, cans, plastic bags etc. Even a mosquito bite from a single mosquito can mete out the disease. The virus is not communicable thus can’t be spread from one person to the other directly. Dengue hemorrhagic fever is a severe form of viral illness. The signs of hemorrhage include bleeding in the nose or gums, black stools, rashes and bruising. This form can be dangerous and can take one’s life.

According to a new research from Imperial College London, published in the May 6 edition of the Journal Science, it has been revealed that some of the human immune system’s defenses through which a person get dengue fever in reality helps in spreading the virus in more cells. This revelation after the research would help in preparing much more powerful vaccine against the dengue virus. The study also focused on the fact that why people at large who get dengue fever the second time have severe and dangerous symptoms. Dengue fever is prevalent in sub-tropical and tropical regions of South East Asia and South America.

With the passage of time the incidence of this fever has increased to a large extent in the last century and now two fifths of the world’s population is at a greater risk from this condition, World Health Organization revealed recently. Till date there is no licensed vaccine available to combat this disease.

This research also identified a set of antibodies, which are created by the human immune system to combat dengue virus, scientists are of the opinion these should not be included in any new vaccine to avert dengue fever. The lead author of the study Professor Gavin Screaton, is of the opinion that a large proportion of the world’s population has risk of getting dengue fever, though its treatment has improved a lot, it could be a painful disease and people are dying from it. But our new research has provided us important information to combat with the dengue virus. Our research will help scientists to create an effective vaccine for this dreaded disease.

Presently there is no special treatment or vaccine available for dengue fever. But precautions like aerosol and liquid spray could be applied directly to the mosquito apart from using mosquito mats and coils.

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